Search results for " Structural dynamics"
showing 7 items of 7 documents
Structural Dynamics and Intentional Governance in Strategic Interorganizational Network Evolution: A Multilevel Approach
2016
This article aims to shed light on the drivers underlying the role and scope of intentional governance of the structural dynamics of whole interorganizational networks. Prior research has distinguished networks that are emergent from networks that are orchestrated. While empirical studies have shown situations in which the role and scope of intentional governance of whole interorganizational networks has changed in time, and there is a growing interest regarding the endogenous drivers of network dynamics, the dimensions that influence intentional governance of network structure dynamics and the way this is carried out remain still to be elucidated. In order to pinpoint these drivers, we le…
The Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobin
2012
International audience; The acknowledged success of the Monod-Wyman-Changeux (MWC) allosteric model stems from its efficacy in accounting for the functional behavior of many complex proteins starting with hemoglobin (the paradigmatic case) and extending to channels and receptors. The kinetic aspects of the allosteric model, however, have been often neglected, with the exception of hemoglobin and a few other proteins where conformational relaxations can be triggered by a short and intense laser pulse, and monitored by time-resolved optical spectroscopy. Only recently the application of time-resolved wide-angle X-ray scattering (TR-WAXS), a direct structurally sensitive technique, unveiled th…
Using synchrotrons and XFELs for time-resolved X-ray crystallography and solution scattering experiments on biomolecules
2015
International audience; Time-resolved structural information is key to understand the mechanism of biological processes, such as catalysis and signalling. Recent developments in X-ray sources as well as data collection and analysis methods are making routine time-resolved X-ray crystallography and solution scattering experiments a real possibility for structural biologists. Here we review the information that can be obtained from these techniques and discuss the considerations that must be taken into account when designing a time-resolved experiment.
Variable Friction Dampers (VFD) for a modulated mitigation of the seismic response of framed structures: Characteristics and design criteria
2022
In this paper a new approach for the energy dissipation is discussed based on the use of Variable Friction Dampers (VFDs). The VFD device is borrowed from braking systems mechanical engineering, able to modulate its capability of dissipation, providing a constant pure friction force coupled with an additional (variable) damping force with the increasing of the displacement. Resorting to a previous study, the characteristics and the efficiency of the “braking” system in terms of reduction of the displacements and the restoring forces is described for SDOF systems under seismic excitations and compared with the performances achievable by classic constant friction dampers (CFDs). Then, a desig…
Seismic behavior of structures equipped with variable friction dissipative (VFD) systems
2021
Usually, to mitigate the stresses in framed structures, different strategies are used. Among them, base isolation, viscous/friction/metallic yielding dampers and tuned mass dumpers have been widely investigated. Fluid Viscous Dampers (FVD) probably result the most diffused for the simplicity in the applications. However, these type of dampers request limited interstorey drifts to avoid dangerous effects. Further, they have an elevate cost. On the contrary, friction dampers are not so expensive but request high interstorey drifts to give a significant contribute in the dissipation of energy during an earthquake. In this paper an approach for the energy dissipation by friction, modified with …
Beating Darwin-Bragg losses in lab-based ultrafast x-ray experiments
2017
The use of low temperature thermal detectors for avoiding Darwin-Bragg losses in lab-based ultrafast experiments has begun. An outline of the background of this new development is offered, showing the relevant history and initiative taken by this work. (C) 2017 Author(s). Funding Agencies|Knut and Alice Wallenberg Foundation; ERC [226136]; Finnish Funding Agency for Technology and Innovation TEKES; Academy of Finland [260880]; NIST Innovations in Measurement Science program; DOE Office of Basic Energy Sciences